產(chǎn)品詳情
簡(jiǎn)單介紹：
Anti-phospho-APC (Ser2054)抗體產(chǎn)品質(zhì)量穩(wěn)定，實(shí)驗(yàn)效果明顯，貨期快，價(jià)格優(yōu)惠，歡迎垂詢訂購(gòu)！我公司長(zhǎng)期供應(yīng)**組化抗體、WB抗體、**組化試劑盒和抗體試驗(yàn)所需全部相關(guān)試劑、熒光標(biāo)記抗體、單克隆抗體、多克隆抗體、各種標(biāo)記的二抗IgG/IgM/IgD/IgA等科研實(shí)驗(yàn)抗體。Anti-phospho-APC (Ser2054)抗體用于**組化實(shí)驗(yàn),WB實(shí)驗(yàn),相應(yīng)的標(biāo)記抗體有HRP標(biāo)記抗體,FITC標(biāo)記,BIO等。
詳情介紹：
Rabbit Anti-phospho-APC (Ser2054)
Cat. Number:
Anti-phospho-APC (Ser2054)抗體KL-12481R
Quantity size:
0.1ml
Concentration:
1mg/ml Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
Tumor suppressor. Promotes rapid degradation of CTNNB1 and participates in Wnt signaling as a negative regulator. APC activity is correlated with its phosphorylation state. Activates the GEF activity of SPATA13 and Anti-phospho-APC (Ser2054)抗體ARHGEF4. Plays a role in hepatocyte growth factor (HGF)-induced cell migration. Required for MMP9 up-regulation via the JNK signaling pathway in colorectal tumor cells. Acts as a mediator of ERBB2-dependent stabilization of microtubules at the cell cortex. It is required for the localization of MACF1 to the cell membrane and this localization of MACF1 is critical for its function in microtubule stabilization.
Also known as:
APC (phospho S2054); Anti-phospho-APC (Ser2054)抗體p-APC (phospho S2054); Adenomatous Polyposis Coli; APC; CC1; DP2; DP2.5; DP3; FAP; FPC; GS; Protein APC.
Specificity:
●
Rabbit Polyclonal IgG, affinity purified by Protein A.
●
Reacts with: Human, Mouse, Rat, Dog, Pig, Cow, Rabbit, Sheep, .
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Immunogen: KLH conjugated synthesised phosphopeptide derived from human APC around the phosphorylation site of Ser2054.
●
Predicted Molecular Weight: 312kDa.
Storage:
Shipped Anti-phospho-APC (Ser2054)抗體at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).
Application:
IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500
Not yet tested in other applications.
Anti-phospho-APC (Ser2054)抗體Optimal working dilutions must be determined by the end user.
Not yet tested in other applications.
Anti-phospho-APC (Ser2054)抗體Optimal working dilutions must be determined by the end user.
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