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產品詳情
  • 產品名稱:Anti-phospho-Ataxin 1(Ser775)抗體

  • 產品型號:磷酸化脊髓小腦失調癥蛋白1抗體
  • 產品廠商:KALANG
  • 產品文檔:
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簡單介紹:
Anti-phospho-Ataxin 1(Ser775)抗體產品質量穩定,實驗效果明顯,貨期快,價格優惠,歡迎垂詢訂購!我公司長期供應**組化抗體、WB抗體、**組化試劑盒和抗體試驗所需全部相關試劑、熒光標記抗體、單克隆抗體、多克隆抗體、各種標記的二抗IgG/IgM/IgD/IgA等科研實驗抗體。Anti-phospho-Ataxin 1(Ser775)抗體用于**組化實驗,WB實驗,相應的標記抗體有HRP標記抗體,FITC標記,BIO等。
詳情介紹:
Rabbit  Anti-phospho-Ataxin 1(Ser775)
Cat. Number:
Anti-phospho-Ataxin 1(Ser775)抗體KL-12534R
Quantity size:
0.1ml
Concentration:
1mg/ml   Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
Ataxin-1, also designated spinocerebellar ataxia type 1 protein (Sca-1), is differentially expressed and localizes toAnti-phospho-Ataxin 1(Ser775)抗體 both the cytoplasm and the nucleus. Mutations in Ataxin-1 are associated with the onset of the autosomal dominant neurodegenerative disorder spinocerebellar ataxia type 1 (SCA-1), which is characterized by progressive neuronal loss in the cerebellum, muscle wasting and ataxia. In Purkinje cells, where SCA-1 is predominantly observed, Ataxin-1 has been shown to directly associate with the Purkinje-enriched leucine-rich acidic nuclear protein (LANP) and the nuclear matrix-associated protein promyelocytic leukemia protein PML. In SCA-1, Ataxin-1 is mutated to encode a polyglutamine protein that forms nuclear aggregates, which interact significantly more strongly with LANP and contribute to the pathogenesis of SCA-1.
Also known as:
Anti-phospho-Ataxin 1(Ser775)抗體Ataxin 1 (phospho S776);p-Ataxin 1 (phospho S776); ATX1; ATXN1; SCA1; Ataxin 1; Ataxin-1; Ataxin1; Spinocerebellar ataxia type 1; ATX1_HUMAN.
Specificity:
Rabbit Polyclonal IgG, affinity purified by Protein A.
Reacts with: Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Sheep, .
Immunogen: KLH conjugated synthesised phosphopeptide derived from human Ataxin 1 around the phosphorylation site of Ser776.
Predicted Molecular Weight: 87kDa.
Storage:
Shipped at 4℃, Anti-phospho-Ataxin 1(Ser775)抗體Store at -20℃ (Avoid repeated freeze/thaw cycles).
Application:
WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  ICC=1:100-500  IF=1:100-500   
Not yet tested in other applications. 
Anti-phospho-Ataxin 1(Ser775)抗體Optimal working dilutions must be determined by the end user.
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